How long should i roast a 10 pound boston butt in the oven?!

Question: i know the grill would be best, but that isn't an option..just wondering how long i should cook it so that it is nice and tender. should i keep it covered the whole time?

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Answers: i know the grill would be best, but that isn't an option..just wondering how long i should cook it so that it is nice and tender. should i keep it covered the whole time?

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Start it out @ 375 for 30 minutes, cover, reduce heat to 225 and cook for 8 - 10 hours. It'll shred nicely.

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20 minutes per pound at oven 350 *

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