What does a hangover mean?!


Question:

What does a hangover mean?

I'm almost positive I know what it is, but just to make sure, what does it mean? Thanks


Answers:
it means you have a severe, painful headache the morning after you drank a lot the night before. your head feels heavier than your body and it throbs when you move.

Hangover
A hangover (veisalgia) describes the sum of unpleasant physiological effects following heavy consumption of alcoholic beverages. The most common reported characteristics of a hangover are headache, nausea, lethargy, sensitivity to light and noise, and thirst.

Hypoglycemia, dehydration, Acetaldehyde intoxication, and vitamin B12 deficiency are all theorized causes of hangover symptoms. Hangovers usually last 12 to 36 hours, although some have been reported to last 48 to 72 hours after alcohol was last consumed.

Symptoms
An alcohol hangover is associated with a variety of symptoms that may include dehydration, fatigue, headache, nausea, vomiting, diarrhea, weakness, elevated body temperature, hypersalivation, difficulty concentrating, anxiety, irritability, sensitivity to light and noise, erratic motor functions and trouble sleeping. Many people will also be repulsed by the thought or taste of alcohol during hangover. The symptoms vary from person to person, and occasion to occasion, usually beginning several hours after drinking. It is not clear whether hangovers affect cognitive abilities.

Causes
Hangovers are multi-causal. Ethanol has a dehydrating effect by causing increased urine production (such substances are known as diuretics), which causes headaches, dry mouth, and lethargy. Dehydration causes the brain to shrink away from the skull slightly. This can be mitigated by drinking water after consumption of alcohol. Alcohol's effect on the stomach lining can account for nausea. Because of the increased NADH production during metabolism of ethanol by the enzymes alcohol dehydrogenase and aldehyde dehydrogenase, excess NADH can build up and slow down gluconeogenesis in the liver, thus causing hypoglycemia.

Another factor contributing to a hangover are the products from the breakdown of ethanol via liver enzymes. Ethanol is converted to acetaldehyde by the enzyme alcohol dehydrogenase, and then from acetaldehyde to acetic acid by the enzyme acetaldehyde dehydrogenase. Acetaldehyde (ethanal) is mildly toxic, contributing to the hangover. These two reactions also require the conversion of NAD+ to NADH. With an excess of NADH, the lactate dehydrogenase reaction is driven to produce lactate from pyruvate (the end product of glycolysis) in order to regenerate NAD+ and sustain life. This diverts pyruvate from other pathways such as gluconeogenesis, thereby impairing the ability of the liver to supply glucose to tissues, especially the brain. Because glucose is the primary energy source of the brain, this lack of glucose contributes to hangover symptoms such as fatigue, weakness, mood disturbances, and decreased attention and concentration.

When one is drinking, the blood vessels in the face, the capillaries, will dilate, giving the person a flushed appearance. When the hangover starts, the capillaries will close up again, contributing to the headache and fatigue that is often experienced in a hangover. Alcohol predisposes inebriated individuals to hypothermia, because of its properties as a vasodilator. When blood vessels are dilated, the blood is closer to the surface of the skin, warming the heat sensing nerves found there. Since the blood is closer to the outside air however, it cools more quickly. A person actually loses body heat faster when intoxicated although they feel warmer.

There are various nervous system effects: the removal of the depressive effects of alcohol in the brain probably account for the light and noise sensitivity.

In addition, it is thought that the presence of other alcohols (such as fusel oils), by-products of the alcoholic fermentation also called congeners, exaggerate many of the symptoms (cogeners may also be zinc or other metals added primarily to sweet liqueurs to enhance their flavor); this probably accounts for the mitigation of the effects when distilled alcohol, particularly vodka, is consumed instead.

The amount of congeners in the drink may also have an effect. Red wines have more congeners than white wines, and some people note less of a hangover with white wine. Some individuals have a strong negative reaction to red wine called Red Wine Headache that can affect them within 15 minutes after drinking a single glass of red wine. The headache is usually accompanied by nausea and flushing.

In alcohol metabolism, one molecule of ethanol (the primary active ingredient in alcoholic beverages) produces 2 molecules of NADH, utilizing Vitamin B12 as a coenzyme. Over-consumption of ethanol may cause vitamin B12 deficiency as well.

Hope this helps! =)

Hi ty_kleine,

You drank yourself silly the night before.
Have a good day. :0)
P.S. all boozer's know the cure is to drink whatever you drank the night before to cure the hangover.

it means when you got drunk, and then the next day you wake up with a headache and you are vomiting and everything you eat makes you want to vomit you dont want to hear nobody talk because you think they are screaming.

In a hangover you have nausea and many different symptoms.Basically a hangover is when you drink various amounts of achohal and we wake up the next day you will probably have a hangover

basically its being dehydrated.

Means your a lightweight

A hangover means you had a hell of a time the night before!

to fell sick after a night of drink hard

p.s. if u want to cure a hang over w/out getting drunk again like drinking a beer drink a vitamin water and go eat at bob evans. works every time (no lie)

It means that you don't want a big fried bologna sandwich anytime soon....

you still hangover your head over the bog and have another puke, and if you cant make the bog hangover the sink and have a puke in there.




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